Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency

BACKGROUND: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that accurately measure virus production following an LRA...

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Bibliografiska uppgifter
I publikationen:EBioMedicine
Huvudupphovsmän: Zerbato, Jennifer M., Khoury, Georges, Zhao, Wei, Gartner, Matthew J., Pascoe, Rachel D., Rhodes, Ajantha, Dantanarayana, Ashanti, Gooey, Megan, Anderson, Jenny, Bacchetti, Peter, Deeks, Steven G., McMahon, James, Roche, Michael, Rasmussen, Thomas A., Purcell, Damian FJ, Lewin, Sharon R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920823/
https://ncbi.nlm.nih.gov/pubmed/33647768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103241
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