Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency

BACKGROUND: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that accurately measure virus production following an LRA...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Zerbato, Jennifer M., Khoury, Georges, Zhao, Wei, Gartner, Matthew J., Pascoe, Rachel D., Rhodes, Ajantha, Dantanarayana, Ashanti, Gooey, Megan, Anderson, Jenny, Bacchetti, Peter, Deeks, Steven G., McMahon, James, Roche, Michael, Rasmussen, Thomas A., Purcell, Damian FJ, Lewin, Sharon R.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920823/
https://ncbi.nlm.nih.gov/pubmed/33647768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103241
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