Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency

Serum and cellular proteins are targets for the formation of adducts with the β-lactam antibiotic amoxicillin. This process could be important for the development of adverse, and in particular, allergic reactions to this antibiotic. In studies exploring protein haptenation by amoxicillin, we observe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Pajares, María A., Zimmerman, Tahl, Sánchez-Gómez, Francisco J., Ariza, Adriana, Torres, María J., Blanca, Miguel, Cañada, F. Javier, Montañez, María I., Pérez-Sala, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065267/
https://ncbi.nlm.nih.gov/pubmed/32210804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00189
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados