Study of Protein Haptenation by Amoxicillin Through the Use of a Biotinylated Antibiotic

Allergic reactions towards β-lactam antibiotics pose an important clinical problem. The ability of small molecules, such as a β-lactams, to bind covalently to proteins, in a process known as haptenation, is considered necessary for induction of a specific immunological response. Identification of th...

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Bibliographic Details
Main Authors: Ariza, Adriana, Collado, Daniel, Vida, Yolanda, Montañez, María I., Pérez-Inestrosa, Ezequiel, Blanca, Miguel, Torres, María José, Cañada, F. Javier, Pérez-Sala, Dolores
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940954/
https://ncbi.nlm.nih.gov/pubmed/24595455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090891
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