JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes

More than 30% of genes in higher eukaryotes are regulated by promoter-proximal pausing of RNA polymerase II (Pol II). Phosphorylation of Pol II CTD by positive transcription elongation factor b (P-TEFb) is a necessary precursor event that enables productive transcription elongation. The exact mechan...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lee, Schuyler, Liu, Haolin, Hill, Ryan, Chen, Chunjing, Hong, Xia, Crawford, Fran, Kingsley, Molly, Zhang, Qianqian, Liu, Xinjian, Chen, Zhongzhou, Lengeling, Andreas, Bernt, Kathrin Maria, Marrack, Philippa, Kappler, John, Zhou, Qiang, Li, Chuan-Yuan, Xue, Yuhua, Hansen, Kirk, Zhang, Gongyi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064345/
https://ncbi.nlm.nih.gov/pubmed/32048991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53930
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados