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Comparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment
Epithelial ovarian carcinoma (EOC) is the most lethal gynecological malignancy. Herein, we sought to determine the efficacy of phosphoinositide 3-kinase (PI3K)/Akt inhibition using three AZD compounds in a NOD-SCID xenograft mouse model and Akt regulation in a panel of eight ovarian cancer cell line...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063971/ https://ncbi.nlm.nih.gov/pubmed/32194423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00206 |
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