COL11A1 confers chemoresistance on ovarian cancer cells through the activation of Akt/c/EBPβ pathway and PDK1 stabilization

Chemoresistance to anticancer drugs substantially reduces survival in epithelial ovarian carcinoma (EOC). Here, microarray analysis showed that collagen type XI alpha 1 (COL11A1) is a chemotherapy response-associated gene. Chemoresistant cells expressed higher COL11A1 and c/EBPβ than chemosensitive...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wu, Yi-Hui, Chang, Tzu-Hao, Huang, Yu-Fang, Chen, Chien-Chin, Chou, Cheng-Yang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695149/
https://ncbi.nlm.nih.gov/pubmed/26087191
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