Effects of lorcaserin on oxycodone self-administration and subjective responses in participants with opioid use disorder

BACKGROUND: Lorcaserin, a high-affinity 5-HT(2C) receptor agonist approved for treating obesity, decreased self-administration of oxycodone and cue-induced reinstatement of drug-seeking behavior in preclinical studies. The current investigation is the first clinical trial to evaluate the ability of...

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Опубликовано в: :Drug Alcohol Depend
Главные авторы: Brandt, Laura, Jones, Jermaine D., Martinez, Suky, Manubay, Jeanne M., Mogali, Shanthi, Ramey, Tatiana, Levin, Frances R., Comer, Sandra D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063580/
https://ncbi.nlm.nih.gov/pubmed/31980285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2020.107859
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