Effects of Ibudilast on the Subjective, Reinforcing, and Analgesic Effects of Oxycodone in Recently Detoxified Adults with Opioid Dependence

Ibudilast, a nonselective phosphodiesterase inhibitor, is used clinically in Asia for the treatment of asthma and poststroke dizziness. Recent preclinical studies have suggested that it also inhibits glial cell activation in rodents, and may alter opioid-mediated effects, including analgesia and wit...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Metz, Verena E, Jones, Jermaine D, Manubay, Jeanne, Sullivan, Maria A, Mogali, Shanthi, Segoshi, Andrew, Madera, Gabriela, Johnson, Kirk W, Comer, Sandra D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520790/
https://ncbi.nlm.nih.gov/pubmed/28393896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.70
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