Lorcaserin suppresses oxycodone self-administration and relapse vulnerability in rats

Opioid use disorder (OUD) is a major public health problem. High relapse rates and poor treatment retention continue to pose major challenges in OUD treatment. Of the abused opioids, oxycodone is well described to maintain self-administration and evoke the durable conditioned responses (“cue reactiv...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Neelakantan, Harshini, Holliday, Erica D., Fox, Robert G., Stutz, Sonja J., Comer, Sandra D., Haney, Margaret, Anastasio, Noelle C., Moeller, F. Gerard, Cunningham, Kathryn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454249/
https://ncbi.nlm.nih.gov/pubmed/28107783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00413
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