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Impact of co-administration of oxycodone and smoked cannabis on analgesia and abuse liability

Cannabinoids combined with opioids produce synergistic antinociceptive effects, decreasing the lowest effective antinociceptive opioid dose (i.e., opioid-sparing effects) in laboratory animals. Although pain patients report greater analgesia when cannabis is used with opioids, no placebo-controlled...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Cooper, Ziva D., Bedi, Gillinder, Ramesh, Divya, Balter, Rebecca, Comer, Sandra D., Haney, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098090/
https://ncbi.nlm.nih.gov/pubmed/29463913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0011-2
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