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Impact of co-administration of oxycodone and smoked cannabis on analgesia and abuse liability
Cannabinoids combined with opioids produce synergistic antinociceptive effects, decreasing the lowest effective antinociceptive opioid dose (i.e., opioid-sparing effects) in laboratory animals. Although pain patients report greater analgesia when cannabis is used with opioids, no placebo-controlled...
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| Veröffentlicht in: | Neuropsychopharmacology |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6098090/ https://ncbi.nlm.nih.gov/pubmed/29463913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0011-2 |
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