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Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells
Long interspersed element-1 (LINE-1, L1) sequences, which comprise about 17% of human genome, are the product of one of the most active types of mobile DNAs in modern humans. LINE-1 insertion alleles can cause inherited and de novo genetic diseases, and LINE-1-encoded proteins are highly expressed i...
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| Publicado en: | Philos Trans R Soc Lond B Biol Sci |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061987/ https://ncbi.nlm.nih.gov/pubmed/32075555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0335 |
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