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Structural variants caused by Alu insertions are associated with risks for many human diseases
Interspersed repeat sequences comprise much of our DNA, although their functional effects are poorly understood. The most commonly occurring repeat is the Alu short interspersed element. New Alu insertions occur in human populations, and have been responsible for several instances of genetic disease...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441760/ https://ncbi.nlm.nih.gov/pubmed/28465436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704117114 |
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