Alu insertion variants alter mRNA splicing

RNA splicing is a highly regulated process dependent on sequences near splice sites. Insertions of Alu retrotransposons can disrupt splice sites or bind splicing regulators. We hypothesized that some common inherited polymorphic Alu insertions are responsible for splicing QTLs (sQTL). We focused on...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Payer, Lindsay M, Steranka, Jared P, Ardeljan, Daniel, Walker, JaNiece, Fitzgerald, Kathryn C, Calabresi, Peter A, Cooper, Thomas A, Burns, Kathleen H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326789/
https://ncbi.nlm.nih.gov/pubmed/30418605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1086
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados