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Altered DNA repair creates novel Alu/Alu repeat‐mediated deletions

Alu elements are the most abundant source of nonallelic homology that influences genetic instability in the human genome. When there is a DNA double‐stranded break, the Alu element's high copy number, moderate length and distance and mismatch between elements uniquely influence recombination pr...

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Dettagli Bibliografici
Pubblicato in:Hum Mutat
Autori principali: Morales, Maria E., Kaul, Tiffany, Walker, JaNiece, Everett, Chelsea, White, Travis, Deininger, Prescott
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068675/
https://ncbi.nlm.nih.gov/pubmed/33675284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.24193
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