Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer

Mammalian genomes are replete with interspersed repeats reflecting the activity of transposable elements. These mobile DNAs are self-propagating, and their continued transposition is a source of both heritable structural variation as well as somatic mutation in human genomes. Tailored approaches to...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Tang, Zuojian, Steranka, Jared P., Ma, Sisi, Grivainis, Mark, Rodić, Nemanja, Huang, Cheng Ran Lisa, Shih, Ie-Ming, Wang, Tian-Li, Boeke, Jef D., Fenyö, David, Burns, Kathleen H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
PNAS Plus
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293032/
https://ncbi.nlm.nih.gov/pubmed/28096347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619797114
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