Human transposon insertion profiling: Analysis, visualization and identification of somatic LINE-1 insertions in ovarian cancer

Mammalian genomes are replete with interspersed repeats reflecting the activity of transposable elements. These mobile DNAs are self-propagating, and their continued transposition is a source of both heritable structural variation as well as somatic mutation in human genomes. Tailored approaches to...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Tang, Zuojian, Steranka, Jared P., Ma, Sisi, Grivainis, Mark, Rodić, Nemanja, Huang, Cheng Ran Lisa, Shih, Ie-Ming, Wang, Tian-Li, Boeke, Jef D., Fenyö, David, Burns, Kathleen H.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293032/
https://ncbi.nlm.nih.gov/pubmed/28096347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619797114
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы