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Somatic retrotransposition is infrequent in glioblastomas

BACKGROUND: Gliomas are the most common primary brain tumors in adults. We sought to understand the roles of endogenous transposable elements in these malignancies by identifying evidence of somatic retrotransposition in glioblastomas (GBM). We performed transposon insertion profiling of the active...

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Detalhes bibliográficos
Publicado no:Mob DNA
Main Authors: Achanta, Pragathi, Steranka, Jared P., Tang, Zuojian, Rodić, Nemanja, Sharma, Reema, Yang, Wan Rou, Ma, Sisi, Grivainis, Mark, Huang, Cheng Ran Lisa, Schneider, Anna M., Gallia, Gary L., Riggins, Gregory J., Quinones-Hinojosa, Alfredo, Fenyö, David, Boeke, Jef D., Burns, Kathleen H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105304/
https://ncbi.nlm.nih.gov/pubmed/27843500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13100-016-0077-5
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