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Dual Inhibitors of 8-Oxoguanine Surveillance by OGG1 and NUDT1
Oxidative damage in DNA is one of the primary sources of mutations in the cell. The activities of repair enzymes 8-oxoguanine DNA glycosylase (OGG1) and human MutT Homologue 1 (NUDT1 or MTH1), which work together to ameliorate this damage, are closely linked to mutagenesis, genotoxicity, cancer, and...
में बचाया:
| में प्रकाशित: | ACS Chem Biol |
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| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061906/ https://ncbi.nlm.nih.gov/pubmed/31622553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00490 |
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