Trifluoperazine prolongs the survival of experimental brain metastases by STAT3-dependent lysosomal membrane permeabilization

Brain metastasis is a major cause of mortality in melanoma patients. The blood-brain barrier (BBB) prevents most anti-tumor compounds from entering the brain, which significantly limits their use in the treatment of brain metastasis. One strategy in the development of new treatments is to assess the...

Full description

Saved in:
Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Zhang, Xin, Ding, Kaikai, Ji, Jianxiong, Parajuli, Himalaya, Aasen, Synnøve Nymark, Espedal, Heidi, Huang, Bin, Chen, Anjing, Wang, Jian, Li, Xingang, Thorsen, Frits
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061752/
https://ncbi.nlm.nih.gov/pubmed/32195026
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items