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Methylated-UHRF1 and PARP1 interaction is critical for homologous recombination

A recent study suggested that methylation of ubiquitin-like with PHD and RING finger domain 1 (UHRF1) is regulated by SET7 and lysine-specific histone demethylase 1A (LSD1) and is essential for homologous recombination (HR). The study demonstrated that SET7-mediated methylation of UHRF1 promotes pol...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Hahm, Ja Young, Kang, Joo-Young, Park, Jin Woo, Jung, Hyeonsoo, Seo, Sang-Beom
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061213/
https://ncbi.nlm.nih.gov/pubmed/31964471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2020.53.2.264
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