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H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation
Histone H3K9 methyltransferase (HMTase) G9a-mediated transcriptional repression is a major epigenetic silencing mechanism. UHRF1 (ubiquitin-like with PHD and ring finger domains 1) binds to hemimethylated DNA and plays an essential role in the maintenance of DNA methylation. Here, we provide evidenc...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402520/ https://ncbi.nlm.nih.gov/pubmed/25765655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv183 |
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