H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation

Histone H3K9 methyltransferase (HMTase) G9a-mediated transcriptional repression is a major epigenetic silencing mechanism. UHRF1 (ubiquitin-like with PHD and ring finger domains 1) binds to hemimethylated DNA and plays an essential role in the maintenance of DNA methylation. Here, we provide evidenc...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Kim, Kee-Beom, Son, Hye-Ju, Choi, Sulji, Hahm, Ja Young, Jung, Hyeonsoo, Baek, Hee Jo, Kook, Hoon, Hahn, Yoonsoo, Kook, Hyun, Seo, Sang-Beom
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402520/
https://ncbi.nlm.nih.gov/pubmed/25765655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv183
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars