Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair

Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is a key epigenetic regulator of DNA methylation maintenance and heterochromatin formation. The roles of UHRF1 in DNA damage repair also have been emphasized in recent years. However, the regulatory mechanism of UHRF1 remains elusive. In this...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hahm, Ja Young, Kim, Ji-Young, Park, Jin Woo, Kang, Joo-Young, Kim, Kee-Beom, Kim, Se-Ryeon, Cho, Hana, Seo, Sang-Beom
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326791/
https://ncbi.nlm.nih.gov/pubmed/30357346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky975
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