Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair

Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is a key epigenetic regulator of DNA methylation maintenance and heterochromatin formation. The roles of UHRF1 in DNA damage repair also have been emphasized in recent years. However, the regulatory mechanism of UHRF1 remains elusive. In this...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Hahm, Ja Young, Kim, Ji-Young, Park, Jin Woo, Kang, Joo-Young, Kim, Kee-Beom, Kim, Se-Ryeon, Cho, Hana, Seo, Sang-Beom
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6326791/
https://ncbi.nlm.nih.gov/pubmed/30357346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky975
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