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UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells
UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is a multi-domain protein associated with cellular proliferation and epigenetic regulation. The UHRF1 binds to methylated CpG dinucleotides and recruits transcriptional repressors DNA methyltransferase 1 (DNMT1) and histone deacetylase...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632929/ https://ncbi.nlm.nih.gov/pubmed/19056828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn961 |
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