UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is a multi-domain protein associated with cellular proliferation and epigenetic regulation. The UHRF1 binds to methylated CpG dinucleotides and recruits transcriptional repressors DNA methyltransferase 1 (DNMT1) and histone deacetylase...

Full description

Saved in:
Bibliographic Details
Main Authors: Kim, Jong Kyong, Estève, Pierre-Olivier, Jacobsen, Steven E., Pradhan, Sriharsa
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632929/
https://ncbi.nlm.nih.gov/pubmed/19056828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn961
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items