A novel requirement for DROSHA in maintenance of mammalian CG methylation

In mammals, faithful inheritance of genomic methylation patterns ensures proper gene regulation and cell behaviour, impacting normal development and fertility. Following establishment, genomic methylation patterns are transmitted through S-phase by the maintenance methyltransferase Dnmt1. Using a pr...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Stathopoulou, Athanasia, Chhetri, Jyoti B., Ambrose, John C., Estève, Pierre-Olivier, Ji, Lexiang, Erdjument-Bromage, Hediye, Zhang, Guoqiang, Neubert, Thomas A., Pradhan, Sriharsa, Herrero, Javier, Schmitz, Robert J., Ooi, Steen K.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766157/
https://ncbi.nlm.nih.gov/pubmed/28934503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx695
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