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Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells
The stochasticity of gene expression presents significant challenges to the modeling of genetic networks. A two-state model describing promoter switching, transcription, and messenger RNA (mRNA) decay is the standard model of stochastic mRNA dynamics in eukaryotic cells. Here, we extend this model t...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060679/ https://ncbi.nlm.nih.gov/pubmed/32071224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910888117 |
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