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A Stochastic Model of Gene Expression with Polymerase Recruitment and Pause Release

Transcriptional bursting is a major source of noise in gene expression. The telegraph model of gene expression, whereby transcription switches between on and off states, is the dominant model for bursting. Recently, it was shown that the telegraph model cannot explain a number of experimental observ...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Cao, Zhixing, Filatova, Tatiana, Oyarzún, Diego A., Grima, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474183/
https://ncbi.nlm.nih.gov/pubmed/32814062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.07.020
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