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A Stochastic Model of Gene Expression with Polymerase Recruitment and Pause Release

Transcriptional bursting is a major source of noise in gene expression. The telegraph model of gene expression, whereby transcription switches between on and off states, is the dominant model for bursting. Recently, it was shown that the telegraph model cannot explain a number of experimental observ...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Cao, Zhixing, Filatova, Tatiana, Oyarzún, Diego A., Grima, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474183/
https://ncbi.nlm.nih.gov/pubmed/32814062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.07.020
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