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Analytical distributions for stochastic gene expression

Gene expression is significantly stochastic making modeling of genetic networks challenging. We present an approximation that allows the calculation of not only the mean and variance, but also the distribution of protein numbers. We assume that proteins decay substantially more slowly than their mRN...

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Detalhes bibliográficos
Main Authors: Shahrezaei, Vahid, Swain, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582303/
https://ncbi.nlm.nih.gov/pubmed/18988743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803850105
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