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Intrinsic and extrinsic contributions to stochasticity in gene expression

Gene expression is a stochastic, or “noisy,” process. This noise comes about in two ways. The inherent stochasticity of biochemical processes such as transcription and translation generates “intrinsic” noise. In addition, fluctuations in the amounts or states of other cellular components lead indire...

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Hlavní autoři: Swain, Peter S., Elowitz, Michael B., Siggia, Eric D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC130539/
https://ncbi.nlm.nih.gov/pubmed/12237400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162041399
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