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Intrinsic and extrinsic contributions to stochasticity in gene expression

Gene expression is a stochastic, or “noisy,” process. This noise comes about in two ways. The inherent stochasticity of biochemical processes such as transcription and translation generates “intrinsic” noise. In addition, fluctuations in the amounts or states of other cellular components lead indire...

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Bibliografiske detaljer
Main Authors: Swain, Peter S., Elowitz, Michael B., Siggia, Eric D.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130539/
https://ncbi.nlm.nih.gov/pubmed/12237400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162041399
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