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Genome-wide analysis of constitutional DNA methylation in familial melanoma

BACKGROUND: Heritable epigenetic alterations have been proposed as an explanation for familial clustering of melanoma. Here we performed genome-wide DNA methylation analysis on affected family members not carrying pathogenic variants in established melanoma susceptibility genes, compared with health...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Salgado, Catarina, Gruis, Nelleke, Heijmans, Bastiaan T., Oosting, Jan, van Doorn, Remco
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060565/
https://ncbi.nlm.nih.gov/pubmed/32143689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00831-7
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