Constitutional promoter methylation and risk of familial melanoma

Constitutional epigenetic changes detected in blood or non-disease involving tissues have been associated with disease susceptibility. We measured promoter methylation of CDKN2A (p16 and p14ARF) and 13 melanoma-related genes using bisulfite pyrosequencing of blood DNA from 114 cases and 122 controls...

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Detalhes bibliográficos
Main Authors: Hyland, Paula L, Burke, Laura S, Pfeiffer, Ruth M, Rotunno, Melissa, Sun, David, Patil, Prasad, Wu, Xiaolin, Tucker, Margaret A, Goldstein, Alisa M, Yang, Xiaohong Rose
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063827/
https://ncbi.nlm.nih.gov/pubmed/24762620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28151
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