Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations

CDKN2A is a major susceptibility gene for cutaneous malignant melanoma (CMM) but the variable penetrance and clinical manifestations among mutation carriers suggest the existence of modifier factors. The goal of this study was to identify modifier genes for CMM in CMM-prone families with or without...

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Main Authors: Yang, Xiaohong Rose, Pfeiffer, Ruth M., Wheeler, William, Yeager, Meredith, Chanock, Stephen, Tucker, Margaret A., Goldstein, Alisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767393/
https://ncbi.nlm.nih.gov/pubmed/19626699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24622
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