Variation in cutaneous patterns of melanomagenesis according to germline CDKN2A/CDK4 status in melanoma-prone families

CDKN2A and CDK4 are well-established melanoma susceptibility genes, but their effect on tumor location/distribution is unknown. We used a case-case study design to assess for differences in tumor location between mutation carriers (CDKN2A =141 patients, 348 melanomas; CDK4 =15 patients, 54 melanomas...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Sargen, Michael R., Pfeiffer, Ruth M., Yang, Xiaohong R., Tucker, Margaret A., Goldstein, Alisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926144/
https://ncbi.nlm.nih.gov/pubmed/31326397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2019.06.138
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