Histologic features of melanoma associated with germline mutations of CDKN2A, CDK4, and POT1 in melanoma-prone families from the United States, Italy, and Spain

BACKGROUND: CDKN2A, CDK4, and POT1 are well-established melanoma-susceptibility genes. OBJECTIVE: We evaluated melanoma histopathology for individuals with germline mutations of CDKN2A, CDK4, and POT1. METHODS: We assessed histopathology for melanomas diagnosed in melanoma-prone families (≥2 individ...

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Detalhes bibliográficos
Publicado no:J Am Acad Dermatol
Main Authors: Sargen, Michael R., Calista, Donato, Elder, David E., Massi, Daniela, Chu, Emily Y., Potrony, Míriam, Pfeiffer, Ruth M., Carrera, Cristina, Aguilera, Paula, Alos, Llucia, Puig, Susana, Elenitsas, Rosalie, Yang, Xiaohong R., Tucker, Margaret A., Landi, Maria Teresa, Goldstein, Alisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505133/
https://ncbi.nlm.nih.gov/pubmed/32283231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaad.2020.03.100
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