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Genome‐wide characterization of 5‐hydoxymethylcytosine in melanoma reveals major differences with nevus
Melanoma demonstrates altered patterns of DNA methylation that are associated with genetic instability and transcriptional repression of numerous genes. Active DNA demethylation is mediated by TET enzymes that catalyze conversion of 5‐methylcytosine (mC) to 5‐hydroxymethylcytosine (hmC). Loss of hmC...
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| Publicado no: | Genes Chromosomes Cancer |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318264/ https://ncbi.nlm.nih.gov/pubmed/32017278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22837 |
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