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DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase

Ferroptosis is a newly characterized form of regulated cell death mediated by iron-dependent accumulation of lipid reactive oxygen species and holds great potential for cancer therapy. However, the molecular mechanisms underlying ferroptosis remain largely elusive. In this study, we define an integr...

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Vydáno v:Nat Commun
Hlavní autoři: Cao, Ji, Chen, Xiaobing, Jiang, Li, Lu, Bin, Yuan, Meng, Zhu, Difeng, Zhu, Hong, He, Qiaojun, Yang, Bo, Ying, Meidan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060199/
https://ncbi.nlm.nih.gov/pubmed/32144268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15109-y
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