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Reprogramming of macrophages employing gene regulatory and metabolic network models

Upon exposure to different stimuli, resting macrophages undergo classical or alternative polarization into distinct phenotypes that can cause fatal dysfunction in a large range of diseases, such as systemic infection leading to sepsis or the generation of an immunosuppressive tumor microenvironment....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Comput Biol
Egile Nagusiak: Hörhold, Franziska, Eisel, David, Oswald, Marcus, Kolte, Amol, Röll, Daniela, Osen, Wolfram, Eichmüller, Stefan B., König, Rainer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059956/
https://ncbi.nlm.nih.gov/pubmed/32097424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007657
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