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Cognate Interaction With CD4(+) T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype

The immunosuppressive tumor microenvironment (TME) established by tumor cells, stromal cells and inhibitory immune cells counteracts the function of tumor reactive T cells. Tumor associated macrophages (TAMs) showing functional plasticity contribute to this process as so called M2-like macrophages c...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Eisel, David, Das, Krishna, Dickes, Elke, König, Rainer, Osen, Wolfram, Eichmüller, Stefan B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395406/
https://ncbi.nlm.nih.gov/pubmed/30853959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00219
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