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Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E

The NT5E (CD73) molecule represents an ecto-5′-nucleotidase expressed on the cell surface of various cell types. Hydrolyzing extracellular adenosine monophosphate into adenosine and inorganic phosphate, NT5E performs numerous homeostatic functions in healthy organs and tissues. Importantly, NT5E can...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kordaß, Theresa, Osen, Wolfram, Eichmüller, Stefan B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915482/
https://ncbi.nlm.nih.gov/pubmed/29720980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00813
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