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Reprogramming of macrophages employing gene regulatory and metabolic network models
Upon exposure to different stimuli, resting macrophages undergo classical or alternative polarization into distinct phenotypes that can cause fatal dysfunction in a large range of diseases, such as systemic infection leading to sepsis or the generation of an immunosuppressive tumor microenvironment....
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7059956/ https://ncbi.nlm.nih.gov/pubmed/32097424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007657 |
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