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P-selectin blockade ameliorates lupus nephritis in MRL/lpr mice through improving renal hypoxia and evaluation using BOLD-MRI

BACKGROUND: Lupus nephritis is one of the most common and severe complications of systemic lupus erythematosus, of which poor prognosis is indicated by aggravated renal hypoxia and tubulointerstitial fibrosis. Cell adhesion molecules play a key role in the progression of lupus nephritis tubulointers...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Zhang, Liwen, Chen, Sheng, Liu, Yan, Xu, Xueqin, Zhang, Qianying, Shao, Shuxin, Wang, Weiming, Li, Xiao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059679/
https://ncbi.nlm.nih.gov/pubmed/32138730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02284-1
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