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P-selectin blockade ameliorates lupus nephritis in MRL/lpr mice through improving renal hypoxia and evaluation using BOLD-MRI

BACKGROUND: Lupus nephritis is one of the most common and severe complications of systemic lupus erythematosus, of which poor prognosis is indicated by aggravated renal hypoxia and tubulointerstitial fibrosis. Cell adhesion molecules play a key role in the progression of lupus nephritis tubulointers...

詳細記述

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書誌詳細
出版年:J Transl Med
主要な著者: Zhang, Liwen, Chen, Sheng, Liu, Yan, Xu, Xueqin, Zhang, Qianying, Shao, Shuxin, Wang, Weiming, Li, Xiao
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059679/
https://ncbi.nlm.nih.gov/pubmed/32138730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02284-1
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