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TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer’s disease

Alzheimer's disease (AD) is one of the most common causes of neurodegenerative diseases in the elderly. The accumulation of amyloid‐β (Aβ) peptides is one of the pathological hallmarks of AD and leads to the impairments of synaptic plasticity and cognitive function. The transient receptor poten...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Du, Yehong, Fu, Min, Huang, Zhilin, Tian, Xin, Li, Junjie, Pang, Yayan, Song, Weihong, Tian Wang, Yu, Dong, Zhifang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059138/
https://ncbi.nlm.nih.gov/pubmed/32061032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13113
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