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MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer’s disease models
Mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1) is an essential negative regulator of MAPKs by dephosphorylating MAPKs at both tyrosine and threonine residues. Dysregulation of the MAPK signaling pathway has been associated with Alzheimer’s disease (AD). However, the role of MKP-1 in A...
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| Publicado no: | Signal Transduct Target Ther |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6895219/ https://ncbi.nlm.nih.gov/pubmed/31840000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0091-4 |
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