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Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

Long-term potentiation (LTP) of synaptic strength between hippocampal neurons is associated with learning and memory, and LTP dysfunction is thought to underlie memory loss. LTP can be temporally and mechanistically classified into decaying (early-phase) LTP and nondecaying (late-phase) LTP. While t...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dong, Zhifang, Han, Huili, Li, Hongjie, Bai, Yanrui, Wang, Wei, Tu, Man, Peng, Yan, Zhou, Limin, He, Wenting, Wu, Xiaobin, Tan, Tao, Liu, Mingjing, Wu, Xiaoyan, Zhou, Weihui, Jin, Wuyang, Zhang, Shu, Sacktor, Todd Charlton, Li, Tingyu, Song, Weihong, Wang, Yu Tian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382266/
https://ncbi.nlm.nih.gov/pubmed/25437879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77888
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