Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

Long-term potentiation (LTP) of synaptic strength between hippocampal neurons is associated with learning and memory, and LTP dysfunction is thought to underlie memory loss. LTP can be temporally and mechanistically classified into decaying (early-phase) LTP and nondecaying (late-phase) LTP. While t...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Dong, Zhifang, Han, Huili, Li, Hongjie, Bai, Yanrui, Wang, Wei, Tu, Man, Peng, Yan, Zhou, Limin, He, Wenting, Wu, Xiaobin, Tan, Tao, Liu, Mingjing, Wu, Xiaoyan, Zhou, Weihui, Jin, Wuyang, Zhang, Shu, Sacktor, Todd Charlton, Li, Tingyu, Song, Weihong, Wang, Yu Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382266/
https://ncbi.nlm.nih.gov/pubmed/25437879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77888
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