Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease that can develop therapy resistance over time. The dense stroma in PDAC plays a critical role in tumor progression and resistance. How this stroma interacts with the tumor cells and how this is influenced by chemotherapy re...

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Publicado en:Transl Oncol
Autores principales: Bulle, Ashenafi, Dekervel, Jeroen, Deschuttere, Lise, Nittner, David, Libbrecht, Louis, Janky, Rekin's, Plaisance, Stéphane, Topal, Baki, Coosemans, An, Lambrechts, Diether, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2020
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058407/
https://ncbi.nlm.nih.gov/pubmed/32145636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.01.004
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