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Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway
Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C is essential for B-cell transformation and development of several B-cell lymphomas particularly those are generated in an immuno-compromised background. EBNA3C recruits ubiquitin-proteasome machinery for deregulating multiple cellular oncoproteins...
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| Publicado en: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7058366/ https://ncbi.nlm.nih.gov/pubmed/32092124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008105 |
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