Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C is essential for B-cell transformation and development of several B-cell lymphomas particularly those are generated in an immuno-compromised background. EBNA3C recruits ubiquitin-proteasome machinery for deregulating multiple cellular oncoproteins...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Gain, Chandrima, Malik, Samaresh, Bhattacharjee, Shaoni, Ghosh, Arijit, Robertson, Erle S., Das, Benu Brata, Saha, Abhik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058366/
https://ncbi.nlm.nih.gov/pubmed/32092124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008105
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