Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C is essential for B-cell transformation and development of several B-cell lymphomas particularly those are generated in an immuno-compromised background. EBNA3C recruits ubiquitin-proteasome machinery for deregulating multiple cellular oncoproteins...

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Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Gain, Chandrima, Malik, Samaresh, Bhattacharjee, Shaoni, Ghosh, Arijit, Robertson, Erle S., Das, Benu Brata, Saha, Abhik
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058366/
https://ncbi.nlm.nih.gov/pubmed/32092124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008105
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